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Clinical Trials

What is clinical research? Clinical research involves experimental studies to determine the safety and effectiveness of medical treatments. Clinical trials rely on the participation of volunteers and involve a research team…

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Alzheimer’s Research Center is committed to the highest level of care for all of our patients. Patients who are enrolled in our studies have access…

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Do you or someone you know suffer from a memory disorder or Alzheimer’s disease? See if you qualify for one of our research studies today! If you or a loved one…

Alzheimer’s Clinical Trials in Albany NY

Current Research Opportunities
For Families
FAQs for Clinical Trials
No Cost Genetic Testing

Dr. Holub has engaged in clinical trials in Alzheimer’s disease for over 34 years. Our clinical research trials include:


  1. Medication treatment trials for Alzheimer’s disease and memory disorders: While the vast majority of such treatment trials at Dr. Holub’s site involves the use of oral medication, occasional trials involve medications which are delivered through subcutaneous injection or periodic intravenous infusions. These programs last various intervals of time running anywhere from six months to a year and a half and are sometimes associated with extension programs, which permit the patient to have access to the actual medication for longer periods, sometimes years.
  2. Some clinical trials involve the development of new imaging procedures for Alzheimer’s disease and other memory disorders, as well as other biomarkers to assist in the identification of patients with this condition.
  3. A third variety of study would involve the collection of epidemiologic data that can be used to learn more about the factors of environment and heredity, which affect the age of onset, course and severity of Alzheimer’s disease.
  4. We also offer intermittent clinical trials directed towards the potential treatment of various symptoms related to Alzheimer’s disease or memory disorders , such as: depression, agitation, anxiety, etc. While it is important to pursue treatments, which may eventually lead to a cure, it is clearly important to develop additional therapies which help patients achieve a better state of well-being today.


Clinical Trial Participation

  • In actuality, Alzheimer’s disease is a broad unrecognized community issue.
  • More than 5.4 million Americans have been diagnosed with Alzheimer’s disease and on average it requires two caregivers per affected individual. That translates to — number of AD patients in our congressional district involving twice that number of caregivers.
  • This is therefore a significant community issue. It does not relate to the interests of one pharmaceutical company or one organization. It becomes a community health issue.

How Can I Enroll in a Clinical Trial?
*Call for a private memory pre-screen appointment
*Speak with a Research Coordinator about medical history and begin medical record review
*Discuss open research studies for which you may qualify based on medical history
*Complete the informed consent process for a study
*Make an appointment for a screening visit with Dr. Holub
*All visits and contact with the Research Office is at no cost to the patient

Current Research Opportunities

The Importance and Benefits of Participating in Alzheimer’s Disease and other Memory Disorders Clinical Trials:

Alzheimer’s disease is a progressive neurological disease, which results in a progressive decline in memory and cognition with a gradual loss of an ability to function independently eventually resulting in a nursing home level of care. Alzheimer’s disease robs people of their most precious commodity, which is that of their personal memories and understanding of their personal relationships. It affects over 5 million Americans and these numbers are rapidly growing, as our population is aging. Most people know someone with Alzheimer’s disease.

For over 35 years we have developed cholinesterase inhibitors, which are able to stabilize the condition for a period of time. They do not cure the condition, but are helpful in the treatment of patients with Alzheimer’s disease. These medications were developed as biochemical knowledge of the condition of Alzheimer’s disease became better known. We are now at a point where we are looking to advance our potential treatments much further. We have identified molecules, such as amyloid and tau, which are involved in the pathophysiology of this disease and we are in the process of developing treatments to eradicate these toxic substances.

Once research medications are designed, developed and studied in the preclinical laboratory, they are then ready to advance to clinical trials in people, first in healthy volunteers and later in patients with Alzheimer’s disease for the purposes of determining if the medications are safe and effective. Clinical trials are required by the FDA (Food and Drug Administration) and involve patient volunteers, who will be assigned various doses of a research medication or a placebo (inactive “sugar pill”) in a “blinded” fashion, such that neither the patient nor the doctor know what treatment the patient is on until the study is completed. Research studies are critical to the development of new treatments for Alzheimer’s disease.

For Families

Why are Clinical Trials So Important To Patients & Their Families?

*Every medication currently approved for the treatment of Alzheimer’s disease has been made possible by patient participation in clinical trials


Clinical Trial Participation Challenges

*AD patients & families are often resigned to the diagnosis unlike cancer patients who often take on a combative attitude to flight to beat it!

*Patients and families are not always aware that clinical trials are an option similar to cancer patients but talks, community outreach and other education programs like this one will help get the message out.

FAQs for Clinical Trials

What is clinical research?

Clinical research involves experimental studies to determine the safety and effectiveness of medical treatments. Clinical trials rely on the participation of volunteers and involve a research team which directly observes the volunteers (also known as research subjects) and collects data about the safety and potential benefits of a medical intervention. Examples of medical interventions include medications, tests and medical devices.

Who sponsors clinical trials?

Clinical trials are sponsored or funded by a variety of organizations including medical institutions, pharmaceutical companies, foundations, physicians and federal agencies such as the National Institute of Health (NIH) and the Department of Veteran’s Affairs (VA).

Is clinical research right the right way to proceed?

Participating in a clinical research trial allows one to take a more active role in his/her medical health as well as potentially having access to treatments that are not available to the general public. While there may or may not be direct benefits to a participant in clinical trials, participation also affords an opportunity to assist in the future of medicine.

Who can participate in a clinical trial?

There are many different types of people who become involved in research. Some individuals are healthy volunteers while others may have known illnesses. Each clinical trial has certain guidelines about who can participate; these are called inclusion and exclusion criteria. Inclusion criteria are those factors which allow a person into the study and exclusion criteria are those that disallow a participant in the trial. Inclusion and exclusion criteria are very important as these guidelines are used to ensure the safety of the participants. It is also important to note that being included or excluded from one trial does not mean that a person may not be eligible for a different trial.

No Cost Genetic Testing

  • Are you between the ages of 50-85?genetic testing albany ny
  • Do you have a first degree family history of memory loss or Alzheimer’s disease?
  • Are you starting to have concerns about memory and cognition?

During your clinic office visit if you are interested in research you may qualify for a FREE test to find out if you are genetically predisposed to Alzhiemer’s disease.

Call for your appointment: 518-426-0575 or email us at

Alzheimer’s Diesase

Alzheimer’s disease is the deterioration of brain cells over time, which causes problems with thinking, behavior, and…

Our MISSION is to find a cure for Alzheimer’s Disease in our lifetime through the pursuit of collaborative research.

Our Method:

To raise public awareness regarding Alzheimer’s Disease through outreach, education and clinical research.

To identify new medications and treatment models through clinical research.

To advocate for patients with Alzheimer’s Disease, as well as to support their families and caregivers.

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